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Do you have a stomach? Do you have difficulty climbing stairs? Is your body mass index (BMI) greater than 25 or greater than 30 kg / m2? If the answer is yes, then you are overweight or rather obese. You need help.
The BMI is the weight in kilograms divided by the size in square meters (kg / m2). The BMI defines people as being overweight (pre-obese) if their BMI is between 25 and 30 kg / m2 and obese when it is greater than 30 kg / m2.
Why does a person whose BMI is greater than 30 kg / m2 need urgent help? Obesity has been associated with all types of cancers, strokes, heart disease, diabetes, arthritis, infertility, erectile dysfunction, kidney damage, to name a few, which ultimately leads to to a decrease in life expectancy.
What is the solution? Weightloss. But losing weight does not come easily. In fact, there is no fast and safe way to lose a few pounds.
Until now, conventional medicine has proposed several methods such as gastric bypass and anti-obesity drugs. But they entail very high costs in terms of unwanted side effects and most often, patients regain lost weight.
But natural medicine has provided inexpensive, accessible and safe solutions to lose weight and maintain a healthy weight.
At the top of the list are regular exercises combined with a diet such as the keto-dietetic diet (high in fat and protein and low in carbohydrates); a mixture of lemon grass, black seeds and turkey; corn silk extract; sweet potato sewage, African bush mango seed extract, beans and turmeric; zobo, bitter melon and bitter leaf among others.
Why exercise is more critical than diet to maintain weight loss
* The morning physical activity can offer more benefits than the routine of the afternoon and evening
A new study from the Anschutz Health and Wellness Center at the University of Colorado (AHWC) at the CU Anschutz Medical Campus in the United States, found that physical activity was more important in maintaining a loss. substantial weight than a diet.
The study was published in the journal Obesity.
The results reveal that people who maintain weight loss successfully must rely on physical activity to maintain their energy balance (rather than a chronic restriction of food intake) in order to avoid regain weight. In the study, people who maintain successful weight loss are people who maintain a reduced weight of 30 pounds or more for more than a year.
The main conclusions are: the total number of calories burned (and consumed) daily by people who maintain their weight gain is significantly higher (300 kcal / day) than that of normal weight individuals, but does not differ not significantly from that of overweight / obese individuals.
Notably, out of the total calories burned, the amount of calories burned during physical activity by those who maintain weight loss is significantly higher (180 kcal / day) compared to that of weight individuals. normal body and overweight individuals / obesity. Despite the higher energy cost associated with the movement of a larger body mass borne by overweight / obese people, people who maintained a weight loss diet burned more energy over the course of the day. 39 physical activity, suggesting that they were moving more.
This is corroborated by the fact that the group of people who maintain weight loss also demonstrated much higher levels of steps per day (12,000 steps per day) compared to participants with normal body weight (9,000 steps per day) and overweight / obese participants (6,500 steps per day).
Meanwhile, in a study, people who worked before noon lost more weight, on average, than those who usually worked out after 3pm.
According to a new study of workouts and waist circumcision, people who exercise in the morning lose more weight than people who do the same workouts later in the day.
The findings help shed light on the thorny question of why some people put considerable weight on exercise and others almost not, and the study adds to the growing body of scientific evidence suggesting that the timing various activities, including exercise, could affect the impact of these activities on us.
Thus, for the new study, published in July in The International Journal of Obesity, the researchers discovered some other differences, possibly significant, between the users of the morning and those of the end of the day. The early exercise group tended to be slightly more active throughout the day, taking more steps in total than those who worked later. They also ate a little less, although the difference is barely 100 calories a day on average. Overall, these differences were barely perceptible.
Lemon, black seeds and turkey lead to weight loss
Researchers have shown how lemons, black seeds and turkeys could be used effectively to induce weight loss because of their anti-obesity effects.
The study titled "Anti-obesity efficacy of selected plants against progesterone-induced obesity" was published in the International Journal of Pharmacy and Biological Sciences.
The study evaluated the anti-obesity efficacy of Citrus limon (lemon), Nigella sativa (black seed) and Cyperous rotundus (hazel) against progesterone-induced obesity in BALB / C mice females. Progesterone was administered subcutaneously and plant extracts were orally administered for 28 days. Food intake and body weight gain were monitored regularly and the lipid profile, neurotransmitters (serotonin and dopamine) playing a key role in energy homeostasis were analyzed.
The results suggest that among the three plants, Citrus limon and Nigella sativa showed a better reduction in circulating free fatty acid levels, a lipid profile leading to a decrease in food intake and body weight gain in female BALB / C mice compared to the progesterone-treated group followed by Cyperous rotundus at a dose of 400 mg / kg body weight (bw). Thus, these plants can be considered as an effective treatment in the management of obesity because of their potential anti-obesity effect.
Rotundus Cyperous is commonly called nutgrass. He calls ayaare and goje at Fula-Fulfulde; ayaa-ayaa, giragiri, girigiri and gwaigwaya in Hausa; naked in Kanuri; and ishoho i toho in Tiv.
Indian researchers concluded, "In general, current results suggest that three different plant extracts possess anti-obesity efficacy against the progesterone-induced obesity model. Citrus limon (400 mg / kg body weight), Nigella sativa (400 mg / kg body weight) followed by
Cyperus rotundus 400 mg / kg body weight showed significant anti-obesity activity.
"The oral administration of these extracts reduced circulating lipid levels, which resulted in a decrease in food intake and body weight in female BALB / C mice, closely resembling lipid levels. human obesity. Thus, it can be considered an effective treatment in the management of obesity because of its potential anti-obesity effect. "
High-corn Corn Silk Extract Reduces Body Weight and Fat Deposition
The researchers demonstrated the effects and mechanisms of action of high corn corn silk extract on body weight and adipose deposits in laboratory animals.
The study published in the journal Nutrition Research and Practice called "High Corn Corn Silk Extract Reduces Body Weight and Fat Deposition in Filled C57BL / 6J Mice". A diet high in fat ".
A total of 30 male, four-week old C57BL / 6J mice were purchased and divided into three groups based on weight using a randomized block model. The normal fat group (NF) received 7% fat (basis of diet weight), the fat rich group (HF) received 25% fat and 0.5% cholesterol, and the high-fat corn silk group (HFCS) high fat diet and high extract of corn silk maysin at a dose of 100 mg / kg body weight daily oral administration. Body weight and body fat were measured, and mRNA expression levels of the proteins involved in the differentiation of fat cells, fat accumulation, fat synthesis, lipolysis and lipoprotein. Oxidation of fat in adipose tissue and liver were measured.
After eight weeks of experimental diet, body weight was significantly lower in the HFCS group compared to the HF group, and the weight of kidney fat and epididymal fat pad was significantly lower in the HFCS group than in the HF group. In the HFCS group, the levels of expression of CCAAT / activator binding protein, peroxisome-γ1 activated receptor-proliferative (PPAR-γ1) and PPAR-γ2 were significantly reduced in adipose tissue epididymal, while the 36 differentiation cluster, lipoprotein lipase, acetyl-CoA carboxylase-1, protein-1c binding sterol regulatory elements, the expression levels of l-39; MRNA of pyruvate dehydrogenase, isozyme 4, glucose-6-phosphate dehydrogenase and stearoyl-CoA desaturase-1 were significantly decreased in liver and adipose. tissue. In the HFCS group, mRNA expression levels of AMP-activated protein kinase, hormone-sensitive lipase, and carnitine palmitoyltransferase-1 were high.
The researchers concluded, "It can be concluded that the high-maysin corn silk extract inhibits the expression of genes involved in the differentiation of fat cells, fat accumulation and synthesis of fat, while promoting the expression of genes involved in lipolysis and fat oxidation, further inhibiting fat accumulation the rise in body weight in laboratory animals. "
Powerful Zobo in the treatment of obesity with an obvious reduction in body weight
The researchers critically examined the effects of the Hibiscus sabdariffa (Roselle / zobo) extract (HSE) on various parameters associated with the development of obesity, such as; the effect of HSE on body weight, the effect of HSE on lipid accumulation, cholesterol metabolism and plasma parameters, the inhibitory effect of HSE on pancreatic lipase and the effect of HSE on differentiation / adipogenesis of adipocytes.
The study published in the journal Molecules called "Beneficial Effects of Natural Bioactive Compounds of Hibiscus sabdariffa L. on Obesity".
This review has collected reports on the various anti-obesity effects of H. sabdariffa bioactive compounds in cellular and animal models, as well as in humans. The available toxicological information on the consumption of H. sabdariffa revealed that its toxicity is dose dependent and may cause adverse effects if administered over a long period of time. Reports have shown that the bioactive compounds derived from H. sabdariffa are effective in the treatment of obesity, with an obvious reduction in body weight, an inhibition of lipid accumulation and a suppression of lactic acidity. adipogenesis by the PPARγ pathway and other transcription factors.
Recently, natural bioactive compounds such as flavonoids and phenols have been shown to be effective in the treatment of obesity. Bioactive compounds in edible plants, such as epigallocatechin gallate (EGCG) green tea, citrus peel nobiletin, turmeric curcumin, resveratrol, pterostilbene berry and anthocyanins from H Sabdariffa, have been reported for their anti-obesity potential in both people in vivo and in vitro studies.
The researchers concluded, "The results consistently indicate that the consumption of HSE reduces body weight, lipid accumulation, and total cholesterol metabolism in animal and human studies. Its effectiveness at inhibiting pancreatic lipase and differentiating adipocytes has also been frequently reported, thus confirming its therapeutic potential in the management of obesity.
"Given that clinical and animal studies have shown that the bioactive compounds of H. sabdariffa are effective in the fight against obesity, it is suggested to use it as an active ingredient incorporated into diets at safe doses .
"The inconsistency of available studies on specific bioactive compounds responsible for the anti-obesogenic properties of H. sabdariffa, as well as effective and safe doses, makes it necessary to continue studies to obtain a more unanimous report."
New bitter melon extract shows metabolic and anti-obesity effects
Extracts of bitter melon seed oil (Momordica charantia) could help reduce body weight, suggests a new Chinese study.
The new bitter melon extract was found to be a rich source of conjugated linolenic acid (CLnA, cis9, trans11, trans13-18: 3) and conjugated linoleic acid (CLA, cis9, trans11-18: 2), and data from a study on animal nutrition revealed a potent anti-obesity effect.
By writing in the Journal of Nutrition & Intermediary Metabolism, researchers reported that completing a high-fat diet with 10 grams per kilogram of innovative bitter melon extract resulted in a significant reduction in body weight compared to animals. receiving only the high-fat diet.
This dose of bitter melon extract was also associated with a lower degree of obesity, but lower doses had no significant effect.
"This beneficial effect was partially interpreted as an increase in lipid metabolism and leptin also participated in the overall regulatory process," they wrote. "It is a detailed exploration of the anti-obesity effect of bitter melon extract, facilitating the rational use of this herbal plant to treat this." more and more serious problem, obesity. "
Bitter leaf caused significant weight loss
The researchers showed how concentrations of bitter leaf leaf extract / Vernonia amygdalina (VA-AEVA and MEVA) resulted in significant weight loss in the rat. They said that the observed weight loss may have been due to the loss of
Adipose / adipose tissue as internal organs have not been affected.
The study titled "The Potentials of Obesity of Aqueous and Methanol Extracts of Vernonia amygdalina" was published in the African Journal of Complementary and Alternative Traditional Medicine.
The study examined the anti-obesity potentials of aqueous and methanol extracts of Vernonia amygdalina in a rat model in which obesity was induced with the help of a diet. high fat food.
Forty-two Wistar rats were randomized into seven groups of six rats each. One group was part of the normal control group and obesity was induced in the other six groups. One of the six groups each served as a positive control and a negative control, while the four groups of tests were designated AEVA100, AEVA500, MEVA50 and MEVA200, respectively. The study lasted
12 weeks after which standard protocols were followed for all analyzes and determinations.
The results show that AEVA and MEVA at the tested concentrations resulted in significant weight loss (without negatively affecting internal organs) and a significant improvement in certain metabolic markers of obesity in the rats tested compared to the negative control rats. MEVA 200 has the greatest anti-obesity effect, while MEVA 50 is the least effective. Whole test extracts compared well with Orlistat as a positive control drug in all respects.
Nigerian researchers concluded: "The benefits of AEVA and MEVA in terms of weight loss are attributable to the rich environment of phytochemicals present in Vernonia amygdalina. Other studies to unlock the mechanisms by which observed weight loss is induced are warranted. "
The researchers concluded, "In conclusion, the anti-obesity potentials of an aqueous solution and a methanol extract of Vernonia amygdalina have been studied in the treatment of obesity in rats with diet high in fat. Both extracts resulted in significant weight loss and significant improvement in some metabolic markers of obesity in test rats compared to negative control rats. The extracts mimicked closely the action of the standard drug, Orlistat.
"The observed effects are probably due to the richness of the breasts of phytochemicals present in the VA. An investigation into the mechanism (s) of action of the extracts is nevertheless justified and continues in our laboratory. "
Black pepper could help fight obesity
Black pepper could help fight obesity, according to new research. Piperonal, a seasoning compound, was found to "significantly" reduce the adverse effects of a high-fat diet in rats. In the Indian study, people who received this supplement for six weeks had lower body weight, lower body fat and blood sugar, and stronger bones compared to animals fed only on food. fat and without pepper.
The study was published in the journal Nutrition and Metabolism. In a separate study, British researchers (UK) from Imperial College London discovered mutations in a gene related to obesity and suggested that "obesity is not not always greediness. It is interesting to note that Indian researchers believe that piperonal could neutralize certain genes associated with severe overweight.
Both teams hope their discoveries will produce a new treatment for obesity, whose rate has nearly tripled in the world since 1975. Botanically called Piper nigrum, black pepper belongs to the family Piperaceae. Local names are unknown. Fruits and seeds are used to treat dyspepsia (indigestion), diarrhea, cholera, clumps, urinary problems, boils, rheumatism, headaches and headaches.
An extract of wild mango seed looks promising in the treatment of obesity
Can eating Ogbono soup help overweight people shed pounds, reduce abdominal fat, lower cholesterol and improve their chances of developing diabetes, heart disease, cancer, stroke, failure? kidney, high blood pressure?
A study published in Lipids in Health and Disease suggests that an extract derived from the seed (Ogbono) of West African mango could help overweight people lose weight, reduce their cholesterol and develop degenerative diseases.
Researchers in other studies have found that Irvingia gabonensis fruit can be used to reduce abdominal fat and to fight against diarrhea and ulcer. Laboratory research has shown that plant seed extracts can inhibit the production of body fat by affecting certain genes and enzymes that regulate metabolism.
A person is said to be obese when the ratio between weight in kilograms and height in square meters, that is, body mass index (BMI), is greater than 30; overweight when the BMI is between 25 and 30; and a healthy weight when the BMI is between 20 and 25. The Irvingia gabonensis seed is the basic ingredient of the delightful popular treat, Ogbono Soup. The fruit looks like a mango, but leaves a bitter aftertaste. The seed, viscous when it touches the water, is used in cooking Ogbono soup.
Botanically known as Irvingia gabonensis, West African mango or wild mango is a commonly consumed fruit in Nigeria, or even in all of West Africa. It is also known as native mango, bush mango, hazelnut and dika breadfruit. In Nigeria, it is pekpeara in Nupe; ugiri (tree or fruit) or ogbono (nucleus or seed) in Igbo; oro (the tree) or aapon (the nucleus) in Yoruba; ogwi (the tree or the fruit) in Benin; the goron or the biri in Hausa; Uyo to Efik.
Aloe vera juice to lose weight?
People looking for quick solutions to lose weight sometimes turn to herbal products, such as those containing aloe vera. Although these products may result in short-term weight loss, they are not likely to result in permanent weight loss and may have a number of side effects, according to the Cleveland Clinic. Most studies on aloe vera and weight loss have used gel or aloe vera supplements rather than aloe vera juice, so it may not have the same effects.
An animal study published in Obesity Research & Practice in December 2008 showed that plant sterols found in Aloe vera could improve body composition. In the study, obese rats that received these plant sterols had lower abdominal fat levels after 35 days than rats that did not receive these sterols. This effect can also occur in people. A small preliminary study published in September 2013 in Nutrition found that obese people with diabetes or prediabetes who were taking an Aloe vera gel complex for eight weeks were losing more weight and body fat than those who did not. They had not received this supplement. Larger longer-term studies are needed to verify these effects.
Sweet potato sewage, African bush mango seed extract, beans, turmeric validated
Japanese researchers have found that starchy sweet potato waste protein suppresses appetite and contains sweet potato peptide (SPP). SPP is produced by enzymatic digestion of proteins in the water during the boiling process.
Researchers in a study published in the journal Heliyon found that after 28 days, mice fed high levels of protein had lost weight, and experts said the results could be replicated at home. # 39; man.
Japanese researchers fed two groups of mice with a high fat diet, which resulted in a higher level of PPS.
After 28 days, the animals were weighed and their liver mass and fat levels were measured. Levels of cholesterol and triglycerides have also been taken, as well as leptin, which controls hunger.
Experts from the National Agriculture and Food Research Organization, Tsukuba, have also collected adiponectin measurements, which measure the metabolic syndrome.
They found that mice that received higher levels of SPP had a significantly lower body weight. They also found that the animals had lower cholesterol, triglyceride, leptin and adiponectin levels.
In addition, one study states that legumes such as beans and peas are the best way to relieve hunger pains. The scientists fed a group of men, either high fiber vegetarian pancakes or high protein veal and pork patties. They found those who ate legumes with 12% fewer calories at their next meal.
The study published in the scientific journal Food & Nutrition is one of the first to compare the impact of meat and legumes on our hunger levels.
As a result, there is little scientific evidence to support claims that vegetables help maintain weight loss. In the study, 43 young men were served at three different meals, consisting mainly of patties. Some had patties of beans and peas, some of veal and pork.
When participants took a high-protein meal made from beans and peas, they consumed 12% fewer calories at the next meal than they had eaten a meal of meat.
The authors added that their study provides welcome evidence in favor of a vegetable-based diet, since meat production weighs much more heavily on our climate than vegetable growing.
In addition, an American study found that the best way to lose excess weight was to eat turmeric-flavored meals. Turmeric is a local spice commonly used for cooking. It looks like ginger with its almost yellow color. It has been used effectively in pain, wounds, diabetes and heart disease.
Turmeric, an Asian spice grown in Nigeria and present in many curries, has a long history of use in reducing inflammation, wound healing and pain relief, preventing diabetes and heart failure, but can it induce weight loss?
According to the results of the animal model study conducted by scientists and colleagues funded by the Agricultural Research Service (ARS), a turmeric compound helped stop the spread of adipose tissue in animal models.
The study published in the Journal of Nutrition hypothesized that dietary curcumin could slow the spread of adipose tissue by inhibiting the growth of new blood vessels, called angiogenesis, necessary for adipose tissue formation.
Curcumin is a bioactive component of curry and turmeric consumed daily in Asian countries for centuries without reported toxic effects.
Turmeric is a spice that comes from the root of Curcuma longa, a member of the ginger family Zingiberaceae.
In Nigeria, it is called atale pupa in Yoruba; gangamau in Hausa; nwandumo in Ebonyi; ohu boboch in Enugu (East Nkanu); gigir at Tiv; magina at Kaduna; turi in the State of Niger; onjonigho at Cross River (Meo tribe).
Eating earlier in the day promotes weight loss by limiting appetite
New research confirms that changing the time of meals in a smaller window, earlier in the day, can contribute to weight loss. This also reveals that weight loss related to this type of meal is probably due to the reduced appetite and hunger hormone, rather than the burning of calories.
An article in the journal Obesity describes an essay that shows how the meal schedule influences metabolism.
The authors wrote: "Eating early in the day, in tune with circadian rhythms, seems to reduce body weight and improve metabolic health."
However, they add that it's not clear what mechanisms might be causing these "weight loss effects".
Therefore, the new study is the "first randomized trial to determine the impact of mealtimes on 24-hour energy metabolism when food intake and meal frequency are matched."
Les chercheurs ont comparé deux groupes de personnes qui prenaient les mêmes trois repas par jour pendant quatre jours, mais à des moments différents: le programme d'alimentation précoce avec restriction de temps (eTRF) et le programme de contrôle.
Au total, 11 hommes et femmes ont terminé l’essai: six dans le groupe eTRF et cinq dans le groupe témoin. Pour pouvoir participer à l'essai, les participants devaient être en bonne santé, âgés de 25 à 45 ans et avoir un excès de poids.
Le groupe eTRF a déjeuné à 8h00 et a pris son dernier repas de la journée à 14h00. Ils ont ensuite jeûné environ 18 heures avant le petit-déjeuner le lendemain.
Le groupe témoin a également déjeuné à 8h00 mais leur dernier repas de la journée était à 20h00. Par conséquent, ils ont jeûné environ 12 heures avant le petit-déjeuner le lendemain.
Les auteurs ont comparé le calendrier de contrôle «à l'heure médiane indiquée pour le petit-déjeuner et le dîner pour les adultes américains».
Le quatrième jour, les participants ont subi une batterie de tests en chambre respiratoire pour mesurer leur métabolisme. Les mesures incluaient les calories brûlées et la quantité de graisse, de glucides et de protéines brûlées.
Les participants ont évalué divers aspects de l'appétit – tels que la faim, le désir, la capacité de manger et la plénitude – en indiquant leur perception de ces mesures sur une échelle mobile.
À partir d’échantillons de sang et d’urine que les participants ont donnés matin et soir, l’équipe a également pu évaluer le taux d’hormones de la faim.
Les résultats ont montré que la combustion des calories ne différait pas beaucoup entre les groupes. Cependant, les participants du programme eTRF présentaient des niveaux inférieurs d'hormone de la faim, la ghréline, et une amélioration de certaines facettes de l'appétit.
Brûlé plus de graisse
Les résultats révèlent également que le groupe eTRF semblait avoir brûlé plus de graisse en 24 heures.
En spéculant sur les raisons pour lesquelles eTRF pourrait favoriser la combustion des graisses, l'équipe suggère que le fait de manger le dernier repas de la journée de l'après-midi pourrait aider le corps à passer de la combustion des glucides à la combustion des graisses pour obtenir de l'énergie.
Cependant, les chercheurs soulignent que les résultats sur la combustion des graisses sont préliminaires et appellent à une étude plus longue pour vérifier et confirmer si des stratégies telles que l'eTRF peuvent aider les personnes à éliminer la graisse corporelle.
Keto Dieters a maintenu la cétose et perdu du poids au cours d'une étude de trois mois
Une nouvelle étude a permis aux chercheurs d'espérer qu'un régime cétogène pourrait s'avérer utile dans l'armée, où l'obésité est un défi permanent, à la fois en termes de recrutement de soldats et de maintien en état de service.
L’étude a été menée à l’Ohio State University, aux États-Unis, auprès de 29 personnes, dont la plupart étaient membres du campus ROTC. Pendant trois mois, 15 des participants ont suivi un régime cétogène et un groupe témoin de 14 pairs a suivi un régime normal.
Les régimes cétogènes sont faibles en glucides et mettent l'accent sur une consommation modérée de protéines, les matières grasses étant consommées jusqu'à satiété. Ils visent à créer un état de cétose nutritionnelle – ce qui se produit lorsque le corps brûle de la graisse, plutôt que des glucides, pour obtenir de l'énergie. Le régime cétogène est souvent utilisé pour contrôler les crises d'épilepsie et est également étudié et appliqué dans divers autres domaines, notamment les sports d'endurance et la gestion du diabète.
Dans l'étude publiée dans la revue Military Medicine, les participants au régime céto ont perdu en moyenne près de 17 livres et ont pu, avec le soutien de conseillers, maintenir une cétose pendant 12 semaines. En tant que groupe, ils ont perdu plus de cinq pour cent de leur graisse corporelle, près de 44 pour cent de leur graisse abdominale ou viscérale et ont amélioré de 48% leur sensibilité à l'insuline – un marqueur qui prédit le risque de diabète.
Le groupe témoin de participants, qui consommaient des régimes contenant au moins 40% de glucides (sur la base de leurs journaux de bord), n’a subi aucun de ces changements.
Les régimes cétogènes de l'étude ne comportaient aucune restriction calorique, mais uniquement des indications sur ce qu'il faut manger et ce qu'il faut éviter. Les glucides ont été limités à environ 30 à 50 grammes par jour, l'accent étant mis sur les noix et les légumes non féculents. De la nourriture était également fournie, soit pour l'épicerie, que les personnes à la diète pourraient utiliser pour préparer leurs repas ou pour des repas congelés préparés à l'avance.
Les participants au régime de céto ont subit des contrôles quasi quotidiens au cours desquels ils ont rapporté des mesures de cétone sanguine à partir d'un test de piqûre au doigt auto-administré et ont reçu une rétroaction, généralement par le biais de messages texte, de l'équipe de recherche. Cétose a été définie comme une concentration sanguine de cétones, produits chimiques fabriqués dans le foie, entre 0,5 et 5,0 mM (millimolaire).
Les deux groupes, dont l'horaire comprenait un entraînement régulier à la résistance, ont montré des niveaux de performance physique comparables à la fin de l'étude. C’était important car il est difficile de perdre du poids sans perdre de la masse musculaire maigre et de la fonction physique.
Les résultats de l'étude sont assortis de réserves. Le groupe qui a suivi le régime cétogène a choisi de faire partie du groupe test, ce que les scientifiques appellent l'auto-sélection. Les études dans lesquelles les participants sont randomisés sont préférées, mais l’équipe de recherche a déclaré vouloir faire cette étude pilote dans un groupe désireux de suivre le régime. Le groupe céto avait également un indice de masse corporelle moyen plus élevé au début de l'étude – 27,9 contre 24,9 dans le groupe de comparaison – ce qui signifie qu'ils avaient plus de graisse à perdre.
Traitement de l'obésité par un régime cétogène à très faible teneur en calories à deux ans: réduction de la graisse viscérale et du fardeau de la maladie
Une étude publiée dans la revue Endocrine a conclu: "En conclusion, un régime cétogène à très faible teneur en calories était efficace 24 mois plus tard, avec une diminution du tissu adipeux viscéral et une réduction de la charge de morbidité individuelle."
L'étude visait à évaluer l'effet à long terme d'un régime alimentaire très hypocalorique-cétogène (VLCK) sur l'excès d'adiposité. Un accent particulier a été mis sur la masse grasse viscérale et son impact sur le fardeau individuel de la maladie. Un groupe de patients obèses (n = 45) a été réparti de manière aléatoire en deux groupes: soit le groupe régime très calorique-cétogène (n = 22), soit un groupe régime diététique faible en calories (n = 23).
Les deux groupes ont reçu un soutien externe. Les paramètres d'adiposité et le nombre cumulé de mois de perte de poids réussie (cinq ou dix pour cent) sur une période de 24 mois ont été quantifiés. Le régime cétogène à très faible teneur en calories a induit moins de deux mois de cétose légère et des effets importants sur le poids corporel à six, 12 et 24 mois. À 24 mois, une tendance à la régression aux niveaux de base a été observée; Cependant, le régime cétogène à très faible teneur en calories induisait une réduction plus importante du poids corporel (−12,5 kg), du tour de taille (−11,6 cm) et de la masse grasse corporelle (−8,8 kg) par rapport au régime hypocalorique (−4,4 kg). , -4,1 cm et -3,8 kg, respectivement).
De manière intéressante, une réduction sélective de la graisse viscérale mesurée par un logiciel spécifique d'analyse par absorptiométrie à rayons X à double énergie (DEXA) (-600 g vs. -202 g) a été observée. Moreover, the very low-calorie-ketogenic diet group experienced a reduction in the individual burden of obesity because of a reduction in disease duration. Very low-calorie-ketogenic diet patients were 500 months with five per cent weight loss vs. the low-calorie diet group (350 months). In conclusion, a very low-calorie-ketogenic diet was effective 24 months later, with a decrease in visceral adipose tissue and a reduction in the individual burden of disease.”